https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45560 Wed 28 Feb 2024 15:21:35 AEDT ]]> Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34208 −8) in combined analyses. A number of these loci contain genes implicated in structure and function of skeletal muscle fibres (ACTG1), neuronal maintenance and signal transduction (PEX14, TGFA, SYT1), or monogenic syndromes with involvement of psychomotor impairment (PEX14, LRPPRC and KANSL1). Mendelian randomization analyses are consistent with a causal effect of higher genetically predicted grip strength on lower fracture risk. In conclusion, our findings provide new biological insight into the mechanistic underpinnings of grip strength and the causal role of muscular strength in age-related morbidities and mortality.]]> Wed 04 Sep 2019 09:48:47 AEST ]]> Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53968 Tue 23 Jan 2024 15:33:56 AEDT ]]>